Experimental research Alginic acid sodium hydrogel co-transplantation with Schwann cells for rat spinal cord repair
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منابع مشابه
Alginic acid sodium hydrogel co-transplantation with Schwann cells for rat spinal cord repair
INTRODUCTION The aim of the study was investigating the influence of Schwann cells-alginic acid sodium hydrogel co-transplantation on a rat model of spinal cord injury. MATERIAL AND METHODS Sprague-Dawley (SD) rats were randomly assigned to 4 groups: control, injury, injury with Schwann cell transplantation, and injury with Schwann cells-alginic acid sodium hydrogel co-transplantation. Gelati...
متن کاملSchwann cells for spinal cord repair.
The complex nature of spinal cord injury appears to demand a multifactorial repair strategy. One of the components that will likely be included is an implant that will fill the area of lost nervous tissue and provide a growth substrate for injured axons. Here we will discuss the role of Schwann cells (SCs) in cell-based, surgical repair strategies of the injured adult spinal cord. We will revie...
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Background: Spinal cord has a limited capacity to repair therefore, medical interventions are necessary for treatment of injuries. Transplantation of Schwann cells has shown a great promising result for spinal cord injury (SCI). However, harvesting Schwann cell has been limited due to donor morbidity and limited expansion capacity. Furthermore, accessible sources such as bone marrow stem cells ...
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Objective: We discussed the repair of spinal cord injury (SCI) in rats by subarachnoid transplantation of Schwann cells (SCs) transfected with bcl-2 gene. Method: Rat spinal cord injury (SCI) were cultured in vitro and transfected with B-cell lymphoma 2 gene (bcl-2 gene) using Ad-EGFP (Enhanced Green Fluorescent Protein) vector. Three groups were set up: control group, negative transfection gro...
متن کاملmesenchymal stem cells as an alternative for schwann cells in rat spinal cord injury
background: spinal cord has a limited capacity to repair therefore, medical interventions are necessary for treatment of injuries. transplantation of schwann cells has shown a great promising result for spinal cord injury (sci). however, harvesting schwann cell has been limited due to donor morbidity and limited expansion capacity. furthermore, accessible sources such as bone marrow stem cells ...
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ژورنال
عنوان ژورنال: Archives of Medical Science
سال: 2012
ISSN: 1734-1922
DOI: 10.5114/aoms.2012.29538